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Tri-o-tolyl phosphate

search CAS: 78-30-8 Element: phosphate tolyl


CAS number
Chemical Name:
Tri-o-tolyl phosphate
Molecular Formula:
C21H21 O4 P
o-cresyl phosphate ; tri-o-tolyl phosphate ; phosphoric acid,tris(2-methylphenyl) ester ; tris(o-cresyl) phosphate ; tris(2-tolyl) phosphate ; tofk ; nclc61041 ; totp ; phosflex179c ; tri-o-cresyl ; tris(o-methylphenyl) phosphate ; tris(o-tolyl)phosphate ; tri-2-cresyl p ; phosphoricacid, tri-o-tolyl ester (8ci) ; plastic x ; triorthocresyl ; phosflex 179c ; tri-o-cresyl phosphate ; tokf ; nsc 438 ; tocp

Product Specifications

Molecular Weight:
368.39 g·mol−1
Melting point:
-25 °C
Boiling point:
410 °C
Flash point:
225 °C
Refractive index:
Physical Description:
clear colorless to yellow viscous liquid

Safety Information

Poison by subcutaneous, intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Most of the cases of tri-o-cresyl phosphate poisoning have followed its ingestion. In 1930, some 15,000 persons were affected in the United States, and of these, 10 died. The responsible material was found to be an alcoholic drink known as Jamaica ginger, or “jake.” This beverage had been adulterated with about 2% of tri-o-cresyl phosphate. The affected persons developed a polyneuritis, which progressed, in many cases, with degeneration of the peripheral motor nerves, the anterior horn cells, and the pyramidal tracts. Sensory changes were absent. Since 1930 there have been several other outbreaks of poisoning following ingestion of the material. Tri-o-cresyl phosphate is more toxic than the m-form, and much more so than tri-p-cresyl phosphate or triphenyl phosphate. Experimental reproductive effects.Combustible when exposed to heat or flame. Can react with oxidizing materials. To fight fire, use CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of POx. See also PHOSPHATES.Analytical Methods: For occupational chemical analysis use NIOSH: Triorthocresyl Phosphate, S209.
Hazard Classes:
Hazard Symbols:
Toxic by ingestion and skin absorption. The o- isomer is highly toxic. TLV: 0.1 mg/m3 (skin); Not Classifiable as a Human Carcinogen.

Europe standard Hazard pictograms, code and definition
Hazardous Substances Data:
Non-Regulated Material ¹
Risk Codes:
51/53-39/23/24/25 (R)
Safety Codes:
61-45-28A-20/21-28 (S)


Global Tri-o-tolyl phosphate Suppliers : Switzerland (1) Germany (1) P.R.China (1)
Sigma-Aldrich International GmbH +41 81 755 28 28 +41 81 755 28 15 Switzerland Get price
Chemos GmbH & Co. KG +49-9402-9336 0 +49-9402-933 613 Germany Get price
Hangzhou Dayangchem Co. Ltd. +86-571-88938639 +86-571-8893-8652 P.R.China Get price

Former or previous provider

The following companies had been manufactured successfully in the past or were listed as an excellent supplier in our directory.
Advance Scientific & Chemical, Inc. ( Fort Lauderdale, FL 33312 USA )
Bullet Success 2016  
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