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Suppliers for
Cirsimaritin
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Properties | CAS |
6601-62-3 | Formula |
C17H14O6 |
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4 Registered suppliers
Molecular Formula: C17H14O6 Hazard Symbols: T,N UN Number: UN 2811 6.1 / PGIII WGKGermany: 3
Description : Cirsimaritin is purified from the herbs of Microtea debilis. Cirsimaritin has the potential use in patients with congestive heart failure that can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. Cirsimaritin inhibits the growth of tumor cells and induces mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), and it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner; support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. - Molecular Weight :314.3
- Boiling Point :563.6±50.0 °C at 760 mmHg
- Purity :98.0%
Molecular Formula : C17H14O6 Canonical SMILES : COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)OC InChI : InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3 InChIKey : ZIIAJIWLQUVGHB-UHFFFAOYSA-N Appearance : Yellow powder Synonyms : Scrophulein; 4',5-Dihydroxy-6,7-dimethoxyflavone; 7-Methylcapillarisin
More details are to be found here
Description : Cirsimaritin is purified from the herbs of Microtea debilis. Cirsimaritin has the potential use in patients with congestive heart failure that can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. Cirsimaritin inhibits the growth of tumor cells and induces mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), and it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner; support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. - Molecular Weight :314.3
- Boiling Point :563.6±50.0 °C at 760 mmHg
- Purity :98.0%
Molecular Formula : C17H14O6 Canonical SMILES : COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)OC InChI : InChI=1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3 InChIKey : ZIIAJIWLQUVGHB-UHFFFAOYSA-N Appearance : Yellow powder Synonyms : Scrophulein; 4',5-Dihydroxy-6,7-dimethoxyflavone; 7-Methylcapillarisin
More details are to be found here
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Properties:
... more properties and specification on Cirsimaritin
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Last update 2024-04-26
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