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BGC > Product Search > Thiamet G | 1009816-48-1
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Suppliers for

Thiamet G



Properties

CAS   1009816-48-1 
Formula   C9H16N2O4

Structure

6 Registered suppliers


Molecular Formula: C9H16N2O4S
Molecular Weight: 248.29934
WGKGermany: 3

Description :
Thiamet G is a potent and selective O-GlcNAcase (OGA) inhibitor with Ki of 21 nM, while exhibiting 37000-fold selectivity over human lysosomal-hexosaminidase. Inhibition of OGA by Thiamet G reduced tau pathology in the brain and total tau in the CSF of rTg4510 mice.
  • Molecular Weight :248.3
  • Purity :> 98%
Molecular Formula :
C9H16N2O4S
Canonical SMILES :
CCN=C1NC2C(C(C(OC2S1)CO)O)O
InChI :
InChI=1S/C9H16N2O4S/c1-2-10-9-11-5-7(14)6(13)4(3-12)15-8(5)16-9/h4-8,12-14H,2-3H2,1H3,(H,10,11)
InChIKey :
PPAIMZHKIXDJRN-UHFFFAOYSA-N
Synonyms :
Thiamet-G; (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol

More details are to be found here
Description :
Thiamet G is a potent and selective O-GlcNAcase (OGA) inhibitor with Ki of 21 nM, while exhibiting 37000-fold selectivity over human lysosomal-hexosaminidase. Inhibition of OGA by Thiamet G reduced tau pathology in the brain and total tau in the CSF of rTg4510 mice.
  • Molecular Weight :248.3
  • Purity :> 98%
Molecular Formula :
C9H16N2O4S
Canonical SMILES :
CCN=C1NC2C(C(C(OC2S1)CO)O)O
InChI :
InChI=1S/C9H16N2O4S/c1-2-10-9-11-5-7(14)6(13)4(3-12)15-8(5)16-9/h4-8,12-14H,2-3H2,1H3,(H,10,11)
InChIKey :
PPAIMZHKIXDJRN-UHFFFAOYSA-N
Synonyms :
Thiamet-G; (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol

More details are to be found here

Detailed information on the suppliers of Thiamet G

Properties:

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