BGC > Product Search > Efinaconazole | 164650-44-6

Molecular Formula: C18H22F2N4O
Molecular Weight: 348.3902864

API
single impurity ≤0.1%，EE ≥99%

Drug Category: ANTI FUNGAL
Site: Virupaksha Organics Ltd

Drug Category: ANTI FUNGAL
Site: Virupaksha Organics Ltd

Drug Category: ANTI FUNGAL
Site: Virupaksha Organics Ltd

Drug Category: ANTI FUNGAL
Site: Virupaksha Organics Ltd

Description :
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes.

• Molecular Weight :348.39
• Purity :> 98%

Molecular Formula :
C18H22F2N4O
Canonical SMILES :
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3
InChI :
InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1
InChIKey :
NFEZZTICAUWDHU-RDTXWAMCSA-N
Synonyms :
KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia.

More details are to be found here

Description :
Efinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14α-demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14α-demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following microorganisms, both in vitro and in clinical infections. Efinaconazole exhibits in vitro minimum inhibitory concentrations (MICs) of 0.06 μg/mL or less against most ( ≥ 90%) isolates of the following microorganisms: Trichophyton rubrum; Trichophyton mentagrophytes.

• Molecular Weight :348.39
• Purity :> 98%

Molecular Formula :
C18H22F2N4O
Canonical SMILES :
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3
InChI :
InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1
InChIKey :
NFEZZTICAUWDHU-RDTXWAMCSA-N
Synonyms :
KP103; KP-103; KP 103; CTK5J2975; AGJ95634; KB145948; AGJ 95634; KB 145948; AGJ-95634; KB-145948; Efinaconazole; trade name: Jublia.

More details are to be found here

MF: C18H22F2N4O
MW: 348,39
other name: Efinaconazole

Purity : 98%
Smile code : C[C@@H](N1CCC(CC1)=C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3
MDL Number : MFCD00936407
MolFormula : C18H22F2N4O
MolWeight : 348.3903
Available in stock : 23.614

More details are to be found here

Smile code:
C[C@@H](N1CCC(CC1)=C)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3
MDL Number:
MFCD00936407
Purity :
98%
Available in stock:
32.207 g

More details are to be found here