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Suppliers for
Bendamustin hydrochloride
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Properties | | CAS |
3543-75-7 | | Formula |
C16H22Cl3N3O2 |
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16 Registered suppliers
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Molecular Formula: C16H22Cl3N3O2 Molecular Weight: 394.72 Hazard Symbols: T,Xn UN Number: UN 2811 6.1 / PGIII WGKGermany: 3 PackingGroup: III HS Code: 29339900
More details are to be found here
Description : Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. - Molecular Weight :394.72
- Melting Point :149-151°C
- Purity :> 98%
Molecular Formula : C16H21Cl2N3O2.HCl Canonical SMILES : CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl InChI : InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
InChIKey :
ZHSKUOZOLHMKEA-UHFFFAOYSA-N
Appearance :
White or Yellowish Crystalline Powder
Synonyms :
SDX-105 (Cytostasane) HCl; SDX 105 (Cytostasane) HCl; SDX105 (Cytostasane) HCl
More details are to be found here
Description : Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. - Molecular Weight :394.72
- Melting Point :149-151°C
- Purity :> 98%
Molecular Formula : C16H21Cl2N3O2.HCl Canonical SMILES : CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl InChI : InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H
InChIKey :
ZHSKUOZOLHMKEA-UHFFFAOYSA-N
Appearance :
White or Yellowish Crystalline Powder
Synonyms :
SDX-105 (Cytostasane) HCl; SDX 105 (Cytostasane) HCl; SDX105 (Cytostasane) HCl
More details are to be found here
Purity : 99% Smile code : Cl.CN1C(CCCC(O)=O)=NC2=C1C=CC(=C2)N(CCCl)CCCl MDL Number : MFCD01658758 MolFormula : C16H22Cl3N3O2 MolWeight : 394.7238 Available in stock : 2.256
More details are to be found here
Purity : 99% Smile code : Cl.CN1C(CCCC(O)=O)=NC2=C1C=CC(=C2)N(CCCl)CCCl MDL Number : MFCD01658758 MolFormula : C16H22Cl3N3O2 MolWeight : 394.7238 Available in stock : 2.256
More details are to be found here
Purity : 99% Smile code : Cl.CN1C(CCCC(O)=O)=NC2=C1C=CC(=C2)N(CCCl)CCCl MDL Number : MFCD01658758 MolFormula : C16H22Cl3N3O2 MolWeight : 394.7238 Available in stock : 2.256
More details are to be found here
Purity : 99% Smile code : Cl.CN1C(CCCC(O)=O)=NC2=C1C=CC(=C2)N(CCCl)CCCl MDL Number : MFCD01658758 MolFormula : C16H22Cl3N3O2 MolWeight : 394.7238 Available in stock : 2.256
More details are to be found here
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Last update 2024-04-29
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