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BGC > Product Search > 3-(1-{3-(5-[(1-Methylpiperidin-4-yl)-methoxy]-pyrimidin-2-yl}-benzyl)-1,6-dihydro-6-oxopyridazin-3-yl)-benzonitrile | 1100598-32-0
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Suppliers for CAS

1100598-32-0


Properties

CAS   1100598-32-0 
Formula   C29H28N6O2 

Structure

7 Registered suppliers


Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C29H28N6O2
Molecular Weight: 492.57162
BOC Sciences USA
Chemos GmbH & Co. KG Germany
Description :
Tepotinib, also known as EMD 1214063 and MSC2156119, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. Tepotinib selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kinase MET (also known as hepatocyte growth factor receptor or HGFR), is the product of the proto-oncogene c-Met and is overexpressed or mutated in many tumor cell types. This protein plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis.
  • Molecular Weight :492.583
  • Boiling Point :626.5±65.0 °C at 760 mmHg
Molecular Formula :
C29H28N6O2
Canonical SMILES :
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
InChI :
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChIKey :
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Appearance :
Solid powder
Synonyms :
EMD-1214063; EMD1214063; EMD 1214063; MSC-2156119; MSC2156119; MSC-2156119
More details are to be found here
Chemtour Biotech Co., Ltd P.R.China
Description :
Tepotinib, also known as EMD 1214063 and MSC2156119, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. Tepotinib selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kinase MET (also known as hepatocyte growth factor receptor or HGFR), is the product of the proto-oncogene c-Met and is overexpressed or mutated in many tumor cell types. This protein plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis.
  • Molecular Weight :492.583
  • Boiling Point :626.5±65.0 °C at 760 mmHg
Molecular Formula :
C29H28N6O2
Canonical SMILES :
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
InChI :
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChIKey :
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Appearance :
Solid powder
Synonyms :
EMD-1214063; EMD1214063; EMD 1214063; MSC-2156119; MSC2156119; MSC-2156119
More details are to be found here
CM Fine Chemicals Switzerland
Description :
Tepotinib, also known as EMD 1214063 and MSC2156119, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. Tepotinib selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kinase MET (also known as hepatocyte growth factor receptor or HGFR), is the product of the proto-oncogene c-Met and is overexpressed or mutated in many tumor cell types. This protein plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis.
  • Molecular Weight :492.583
  • Boiling Point :626.5±65.0 °C at 760 mmHg
Molecular Formula :
C29H28N6O2
Canonical SMILES :
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
InChI :
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChIKey :
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Appearance :
Solid powder
Synonyms :
EMD-1214063; EMD1214063; EMD 1214063; MSC-2156119; MSC2156119; MSC-2156119
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Tepotinib, also known as EMD 1214063 and MSC2156119, is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. Tepotinib selectively binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. The receptor tyrosine kinase MET (also known as hepatocyte growth factor receptor or HGFR), is the product of the proto-oncogene c-Met and is overexpressed or mutated in many tumor cell types. This protein plays key roles in tumor cell proliferation, survival, invasion, and metastasis, and tumor angiogenesis.
  • Molecular Weight :492.583
  • Boiling Point :626.5±65.0 °C at 760 mmHg
Molecular Formula :
C29H28N6O2
Canonical SMILES :
CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC(=CC=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
InChI :
InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,17-18,21H,10-13,19-20H2,1H3
InChIKey :
AHYMHWXQRWRBKT-UHFFFAOYSA-N
Appearance :
Solid powder
Synonyms :
EMD-1214063; EMD1214063; EMD 1214063; MSC-2156119; MSC2156119; MSC-2156119
More details are to be found here


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