BGC > Product Search > Epz015866 | 1616391-87-7

Molecular Formula: C22H28N4O2

Molecular Formula: C22H28N4O2

Description :
EPZ015866,also called as GSK591, is a chemical probe for PRMT5 which has a role in diverse cellular processes including tumorigenesis. It exhibits excellent selectivity against a panel of methyltransferases. Inhibits the PRMT5/MEP50 complex from methylati

• Molecular Weight :380.48
• Boiling Point :648.4±55.0 °C | Condition: Press: 760 Torr

Molecular Formula :
C22H28N4O2
Canonical SMILES :
C1CC(C1)NC2=NC=CC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O
InChI :
1S/C22H28N4O2/c27-20(15-26-11-9-16-4-1-2-5-18(16)14-26)13-24-22(28)17-8-10-23-21(12-17)25-19-6-3-7-19/h1-2,4-5,8,10,12,19-20,27H,3,6-7,9,11,13-15H2,(H,23,25)(H,24,28)/t20-/m0/s1
InChIKey :
TWKYXZSXXXKKJU-FQEVSTJZSA-N
Solubility :
DMSO,76 mg/mL (199.74 mM); Ethanol, 76 mg/mL (199.74 mM); Water, <1 mg/mL (<1 mM);
Appearance :
Solid powder
Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -28℃ for long term (months to years).
Synonyms :
GSK591; GSK-591; GSK 591; EPZ015866; EPZ-015866; EPZ 015866; GSK 3203591; GSK-3203591; GSK3203591; 2-(cyclobutylamino)-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyridine-4-carboxamideEPZ015866GSK591GTPL8954SCHEMBL16220740GSK32035912-(cyclobutylamino)-N-[(2S)-2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]pyridine-4-carbo

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