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Suppliers for CAS
3351-86-8
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Properties | | CAS |
3351-86-8 | | Formula |
C42H58O6 |
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19 Registered suppliers
Simagchem Corporation
P.R.China
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Sancai Industry Co.,Ltd.
P.R.China
| Appearance | Light yellow green powder
| | Flavor | Characteristic
| | Particle size | 100% pass through 80 mesh
| | Extract Solvents | Water and Ethanol
| | Tests |
| | Loss on drying | ≤ 5.0%
| | Ash (3h at 600℃ ) | ≤ 5.0%
| | Heavy metals |
| | Lead content | ≤ 3ppm
| | Cadmium content | ≤ 1ppm
| | Arsenic content | ≤ 1ppm
| | Mercury content | ≤ 0.1ppm
| | Residual Solvents | ≤ 50ppm
| | Residual Pesticide | Negative
| | Fucoxanthin (UV) | Fucoxanthin ≥ 20.0%
| | Microbial |
| | Total bacterial count | Max. 1000cfu/g
| | Yeast ＆ Mould | Max. 100cfu/g
| | Coliforms | <10cfu/g
| | Escherichia coli | Negative
| | Salmonella | Negative |
H&Z Industry Co.,Ltd
P.R.China
Appearance： Light yellow green powder | Flavor： Characteristic | Particle size： 100% pass through 80 mesh | Extract Solvents Water and Ethanol |
Tests
Loss on drying： ≤ 5.0% | Ash (3h at 600℃ )： ≤ 5.0% |
Heavy metals
Lead content： ≤ 3ppm | Cadmium content： ≤ 1ppm | Arsenic content： ≤ 1ppm | Mercury content： ≤ 0.1ppm | Residual Solvents： ≤ 50ppm | Residual Pesticide： Negative | Fucoxanthin (UV)： Fucoxanthin ≥ 20.0%
Microbial
Total bacterial count： Max. 1000cfu/g | Yeast ＆ Mould： Max. 100cfu/g | Coliforms： <10cfu/g | Escherichia coli： Negative | Salmonella： Negative
Xingrui Industry Co., Limited
P.R.China
Appearance： Light yellow green powder | Flavor： Characteristic | Particle size： 100% pass through 80 mesh | Extract Solvents Water and Ethanol |
Tests
Loss on drying： ≤ 5.0% | Ash (3h at 600℃ )： ≤ 5.0% |
Heavy metals
Lead content： ≤ 3ppm | Cadmium content： ≤ 1ppm | Arsenic content： ≤ 1ppm | Mercury content： ≤ 0.1ppm | Residual Solvents： ≤ 50ppm | Residual Pesticide： Negative | Fucoxanthin (UV)： Fucoxanthin ≥ 20.0%
Microbial
Total bacterial count： Max. 1000cfu/g | Yeast ＆ Mould： Max. 100cfu/g | Coliforms： <10cfu/g | Escherichia coli： Negative | Salmonella： Negative
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Appearance： Light yellow green powder | Flavor： Characteristic | Particle size： 100% pass through 80 mesh | Extract Solvents Water and Ethanol |
Tests
Loss on drying： ≤ 5.0% | Ash (3h at 600℃ )： ≤ 5.0% |
Heavy metals
Lead content： ≤ 3ppm | Cadmium content： ≤ 1ppm | Arsenic content： ≤ 1ppm | Mercury content： ≤ 0.1ppm | Residual Solvents： ≤ 50ppm | Residual Pesticide： Negative | Fucoxanthin (UV)： Fucoxanthin ≥ 20.0%
Microbial
Total bacterial count： Max. 1000cfu/g | Yeast ＆ Mould： Max. 100cfu/g | Coliforms： <10cfu/g | Escherichia coli： Negative | Salmonella： Negative
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
Sigma-Aldrich International GmbH
Switzerland
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
New Natural Biotechnology Co.,Ltd.
P.R.China
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
Arakato Development Ltd
Hong Kong
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
FUDAW INDUSTRY LTD
P.R.China
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
Nantong Xindao Biotech Ltd
P.R.China
Molecular Formula: C42H58O6 Molecular Weight: 658.91 Hazard Symbols: F UN Number: UN1170 - class 3 - PG 2 - Ethanol, solution WGKGermany: 3 HS Code: 29153900
More details are to be found here
Zehao Industry Co., Ltd.
P.R.China
Finetech Industry Limited
P.R.China
More details are to be found here
Xiamen Equation Chemical Co.,Ltd
P.R.China
More details are to be found here
Chemos GmbH & Co. KG
Germany
More details are to be found here
BuGuCh & Partners
Germany
More details are to be found here
Xi´an SR Bio-Engineering Co., Ltd.
P.R.China
Introduction to Fucoxanthin
Fucoxanthin, is a pigment contained in brown algae diatoms, golden algae and yellow-green algae, which participates in the photochemical system II of photosynthesis.
Pharmacological action
1. Anti-tumor effect
(1) Skin cancer
Fucoxanthin can inhibit the enhancement of mouse epidermal ornithine decarboxylase activity induced by tetradecanoylphorbol-13-acetate (TPA), a strong skin carcinogen, and can also inhibit TPA-induced human herpes The virus activates, thereby inhibiting skin tumors induced by TPA.
(2) Colon cancer
Fucoxanthin has an inhibitory effect on the formation of duodenal cancer induced by N-ethyl-N\'-nitro-N-nitrosoguanidine. Fucoxanthin can significantly inhibit the growth of colon cancer cell lines, including Caco-2, HT-29 and DLD-1. Induces DNA fragmentation in colon cancer cells, promotes cell apoptosis, and inhibits the expression of apoptosis-related protein Bcl-2.
Fucoxanthin can inhibit the proliferation of human colon cancer cell line WiDr in a dose-dependent manner, block the cell cycle in G0/G1 phase, and induce apoptosis.
(3) Tumors of the blood system
The effect of fucoxanthin on acute myeloid leukemia HL-60 cell line. Fucoxanthin can significantly inhibit the proliferation of HL-60 cells. The effect of fucoxanthin on adult T lymphocyte leukemia. Fucoxanthin and its metabolite fucoxanthin can inhibit the survival of human T-cell lymphotropic virus type 1 (HTLV-1) infected T cells and adult T-cell leukemia cells.
(4) Prostate cancer
Fucoxanthin can significantly reduce the survival rate of prostate cancer cells and induce cell apoptosis. Both fucoxanthin and its metabolite fucoxanthin can inhibit the proliferation of PC-3 cells, activate Caspase-3 and induce apoptosis.
(5) Liver cancer
Fucoxanthin has an inhibitory effect on the growth of human liver cancer HepG2 cells, can block cells in the G0/G1 phase, and inhibit the phosphorylation of Rb protein Ser780 site.
2. Antioxidant effect
Fucoxanthin has a good antioxidant effect, even better than vitamin E and vitamin C. Fucoxanthin has a protective effect on human fiber cell damage caused by UV-B. The antioxidant effect of fucoxanthin is mainly through regulating the activity of Na+-K+-ATPase, and regulating the activity of cata lase and glutathione in tissues and molecules caused by the lack of retinol.
3. Anti-inflammatory effect
Fucoxanthin has an inhibitory effect on the exudation of endotoxin-induced inflammatory mediators, and is in a dose-dependent relationship. Its anti-inflammatory effect is equivalent to prednisolone, indicating that fucoxanthin can permeate inflammation induced by endotoxin in mice , NO, PGE2 and tumor necrosis factor have a certain inhibitory effect. Its anti-inflammatory effect is mainly by inhibiting the exudation of NO from the inflammatory reaction caused by lipopolysaccharide-induced macrophages. RT-PCR analysis shows that the mRNA of NO synthase and cyclooxygenase is inhibited by fucoxanthin, and, Tumor necrosis factor, interleukin IL-1β and IL-6, and mRNA survivin expression are all inhibited by fucoxanthin in a dose-dependent relationship. These results indicate that fucoxanthin may have a variety of inflammatory responses Has an important role.
4. Lose weight
Fucoxanthin can eliminate fat accumulation in two ways. Fucoxanthin can activate a protein called UCP1, which promotes lipolysis. At the same time, it can also stimulate the liver to produce DHA, which lowers cholesterol levels.
5. Other
Sea urchin diet seaweed contains fucoxanthin, which has a significant effect on the phagocytic ability and ovulation of macrophages.
Santa Cruz Biotechnology, Inc.
USA
Introduction to Fucoxanthin
Fucoxanthin, is a pigment contained in brown algae diatoms, golden algae and yellow-green algae, which participates in the photochemical system II of photosynthesis.
Pharmacological action
1. Anti-tumor effect
(1) Skin cancer
Fucoxanthin can inhibit the enhancement of mouse epidermal ornithine decarboxylase activity induced by tetradecanoylphorbol-13-acetate (TPA), a strong skin carcinogen, and can also inhibit TPA-induced human herpes The virus activates, thereby inhibiting skin tumors induced by TPA.
(2) Colon cancer
Fucoxanthin has an inhibitory effect on the formation of duodenal cancer induced by N-ethyl-N\'-nitro-N-nitrosoguanidine. Fucoxanthin can significantly inhibit the growth of colon cancer cell lines, including Caco-2, HT-29 and DLD-1. Induces DNA fragmentation in colon cancer cells, promotes cell apoptosis, and inhibits the expression of apoptosis-related protein Bcl-2.
Fucoxanthin can inhibit the proliferation of human colon cancer cell line WiDr in a dose-dependent manner, block the cell cycle in G0/G1 phase, and induce apoptosis.
(3) Tumors of the blood system
The effect of fucoxanthin on acute myeloid leukemia HL-60 cell line. Fucoxanthin can significantly inhibit the proliferation of HL-60 cells. The effect of fucoxanthin on adult T lymphocyte leukemia. Fucoxanthin and its metabolite fucoxanthin can inhibit the survival of human T-cell lymphotropic virus type 1 (HTLV-1) infected T cells and adult T-cell leukemia cells.
(4) Prostate cancer
Fucoxanthin can significantly reduce the survival rate of prostate cancer cells and induce cell apoptosis. Both fucoxanthin and its metabolite fucoxanthin can inhibit the proliferation of PC-3 cells, activate Caspase-3 and induce apoptosis.
(5) Liver cancer
Fucoxanthin has an inhibitory effect on the growth of human liver cancer HepG2 cells, can block cells in the G0/G1 phase, and inhibit the phosphorylation of Rb protein Ser780 site.
2. Antioxidant effect
Fucoxanthin has a good antioxidant effect, even better than vitamin E and vitamin C. Fucoxanthin has a protective effect on human fiber cell damage caused by UV-B. The antioxidant effect of fucoxanthin is mainly through regulating the activity of Na+-K+-ATPase, and regulating the activity of cata lase and glutathione in tissues and molecules caused by the lack of retinol.
3. Anti-inflammatory effect
Fucoxanthin has an inhibitory effect on the exudation of endotoxin-induced inflammatory mediators, and is in a dose-dependent relationship. Its anti-inflammatory effect is equivalent to prednisolone, indicating that fucoxanthin can permeate inflammation induced by endotoxin in mice , NO, PGE2 and tumor necrosis factor have a certain inhibitory effect. Its anti-inflammatory effect is mainly by inhibiting the exudation of NO from the inflammatory reaction caused by lipopolysaccharide-induced macrophages. RT-PCR analysis shows that the mRNA of NO synthase and cyclooxygenase is inhibited by fucoxanthin, and, Tumor necrosis factor, interleukin IL-1β and IL-6, and mRNA survivin expression are all inhibited by fucoxanthin in a dose-dependent relationship. These results indicate that fucoxanthin may have a variety of inflammatory responses Has an important role.
4. Lose weight
Fucoxanthin can eliminate fat accumulation in two ways. Fucoxanthin can activate a protein called UCP1, which promotes lipolysis. At the same time, it can also stimulate the liver to produce DHA, which lowers cholesterol levels.
5. Other
Sea urchin diet seaweed contains fucoxanthin, which has a significant effect on the phagocytic ability and ovulation of macrophages.
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