BGC > Product Search > Tectorigenin | 548-77-6

Molecular Formula: C16H12O6
Molecular Weight: 300.26
WGKGermany: 3

Molecular Formula: C16H12O6
Molecular Weight: 300.26
WGKGermany: 3

Description :
Tectorigenin induced differentiation of human promyelocytic leukemia HL-60 cells to granulocytes and monocytes/macrophages, and caused apoptotic changes of DNA in the cells, as did genistein. Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF and decreased the expression of Bcl-2 protein, with less activity than genistein. From these results, tectorigenin may be a possible therapeutic agent for leukemia.

• Molecular Weight :300.26
• Boiling Point :601.5±55.0 °C at 760 mmHg
• Melting Point :225-226°C
• Purity :> 98%

Molecular Formula :
C16H12O6
Canonical SMILES :
COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O
InChI :
InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
InChIKey :
OBBCRPUNCUPUOS-UHFFFAOYSA-N
Solubility :
Soluble in DMSO
Appearance :
White to Orange to Green Powder to Crystal
Application :
Antioxidant.
Storage : Store at 2-8°C
Synonyms :
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-; Isoflavone, 4',5,7-trihydroxy-6-methoxy-; 5,7,4'-Trihydroxy-6-methoxyisoflavone; K 251T; Tectrigenin

More details are to be found here

Description :
Tectorigenin induced differentiation of human promyelocytic leukemia HL-60 cells to granulocytes and monocytes/macrophages, and caused apoptotic changes of DNA in the cells, as did genistein. Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF and decreased the expression of Bcl-2 protein, with less activity than genistein. From these results, tectorigenin may be a possible therapeutic agent for leukemia.

• Molecular Weight :300.26
• Boiling Point :601.5±55.0 °C at 760 mmHg
• Melting Point :225-226°C
• Purity :> 98%

Molecular Formula :
C16H12O6
Canonical SMILES :
COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O
InChI :
InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
InChIKey :
OBBCRPUNCUPUOS-UHFFFAOYSA-N
Solubility :
Soluble in DMSO
Appearance :
White to Orange to Green Powder to Crystal
Application :
Antioxidant.
Storage : Store at 2-8°C
Synonyms :
5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-; Isoflavone, 4',5,7-trihydroxy-6-methoxy-; 5,7,4'-Trihydroxy-6-methoxyisoflavone; K 251T; Tectrigenin

More details are to be found here