|
Suppliers for CAS
211555-08-7
|
Properties | | CAS |
211555-08-7 | | Formula |
C16H15N3O3 |
|
4 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C16H15N3O3
Molecular Weight: 297.3086
Aea.ltd
P.R.China
Molecular Formula: C16H15N3O3
Molecular Weight: 297.3086
BOC Sciences
USA
Description : WHI-P180 moderately inhibited ABCG2 function, exhibiting weak phototoxicity. The elimination half-life of WHI-P180 in CD-1 mice (BALB/ c mice) following i.v., i.p., or p.o. administration was less than 10 min. Systemic clearance of WHI-P180 was 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic i.p. bolus doses of 25 mg/kg, inhibited IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis. Molecular Formula : C16H15N3O3 Canonical SMILES : COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC InChI : InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
InChIKey :
BNDYIYYKEIXHNK-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Synonyms :
WHI-P180; WHI-P-180; WHI-P 180; 3-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol; Janex 3; WHI-P 180; WHIP180
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : WHI-P180 moderately inhibited ABCG2 function, exhibiting weak phototoxicity. The elimination half-life of WHI-P180 in CD-1 mice (BALB/ c mice) following i.v., i.p., or p.o. administration was less than 10 min. Systemic clearance of WHI-P180 was 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic i.p. bolus doses of 25 mg/kg, inhibited IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis. Molecular Formula : C16H15N3O3 Canonical SMILES : COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC InChI : InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
InChIKey :
BNDYIYYKEIXHNK-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Synonyms :
WHI-P180; WHI-P-180; WHI-P 180; 3-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol; Janex 3; WHI-P 180; WHIP180
More details are to be found here
|
details
details