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BGC > Product Search > Ispinesib | 336113-53-2
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Suppliers for CAS

336113-53-2



 

Properties

CAS   336113-53-2 
Formula   C30H33ClN4O2 

Structure

10 Registered suppliers


Amadis Chemical Company Limited P.R.China
Dayang Chem (Hangzhou) Co.,Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C30H33ClN4O2
Molecular Weight: 517.08
More details are to be found here
Molecular Formula: C30H33ClN4O2
Molecular Weight: 517.08
More details are to be found here
Finetech Industry Limited P.R.China
Hangzhou Lingrui Chemical Co., Ltd. P.R.China

More details are to be found here
BOC Sciences USA
Chemos GmbH & Co. KG Germany
Description :
Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be less likely to cause the peripheral neuropathy often associated with the tubulin-targeting agents.
  • Molecular Weight :517.07
Molecular Formula :
C30H33ClN4O2
Canonical SMILES :
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChI :
InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
InChIKey :
QJZRFPJCWMNVAV-HHHXNRCGSA-N
Synonyms :
SB-715992; SB715992; SB 715992; CK 0238273; CK-0238273; CK0238273.
More details are to be found here
Alpha Biopharmaceuticals Co., Ltd. P.R.China
Description :
Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be less likely to cause the peripheral neuropathy often associated with the tubulin-targeting agents.
  • Molecular Weight :517.07
Molecular Formula :
C30H33ClN4O2
Canonical SMILES :
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChI :
InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
InChIKey :
QJZRFPJCWMNVAV-HHHXNRCGSA-N
Synonyms :
SB-715992; SB715992; SB 715992; CK 0238273; CK-0238273; CK0238273.
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be less likely to cause the peripheral neuropathy often associated with the tubulin-targeting agents.
  • Molecular Weight :517.07
Molecular Formula :
C30H33ClN4O2
Canonical SMILES :
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C
InChI :
InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1
InChIKey :
QJZRFPJCWMNVAV-HHHXNRCGSA-N
Synonyms :
SB-715992; SB715992; SB 715992; CK 0238273; CK-0238273; CK0238273.
More details are to be found here

Detailed information on the suppliers of Ispinesib

Properties:

... more properties and specification on Ispinesib
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