BGC > Product Search > Cisapride | 81098-60-4

Molecular Formula: C23H29ClFN3O4
Molecular Weight: 465.95
Hazard Symbols: Xi
WGKGermany: 2

Molecular Formula: C23H29ClFN3O4
Molecular Weight: 465.95
Hazard Symbols: Xi
WGKGermany: 2

Molecular Formula: C23H29ClFN3O4
Molecular Weight: 465.95
Hazard Symbols: Xi
WGKGermany: 2

Description :
Cisapride is a drug that increases motility in the upper gastrointestinal tract and is used as a Gastroprokinetic. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. It is also a potent human ether-à-go-go-related gene (hERG) potassium channel inhibitor. It showed higher inhibitory effects on a hERG current with IC50 of 9.4 × 10-9 M in vitro. It inhibited Kv4.3 in a concentration-dependent manner with IC50 values of 9.8 uM. It could not bring about more colitis damages through 5HT(4) receptors. It was discovered by Janssen Pharmaceutica in 1980. It has been withdrawn from the market.

• Molecular Weight :465.95
• Boiling Point :605.4±55.0 °C | Condition: Press: 760 Torr
• Melting Point :109.8 °C
• Purity :> 99 %

Molecular Formula :
C23H29ClFN3O4
Canonical SMILES :
COC1CN(CCC1NC(=O)C2=CC(=C(C=C2OC)N)Cl)CCCOC3=CC=C(C=C3)F
InChI :
InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)/t20-,22+/m0/s1
InChIKey :
DCSUBABJRXZOMT-RBBKRZOGSA-N
Solubility :
10 mM in H2O (free soluble)
Appearance :
White to slightly beige powder
Application :
Anti-ulcer agents; gastrointestinal agents; serotonin agonists
Storage : Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Synonyms :
Rel-Cisapride; R 51619; (±)-Cisapride

More details are to be found here

Purity : 98%
Smile code : O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number : MFCD00869327
MolFormula : C23H29ClFN3O4
MolWeight : 465.9455
Available in stock : 350.158

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here

Smile code:
O=C(C1=CC(Cl)=C(C=C1OC)N)N[C@@H]2[C@@H](CN(CC2)CCCOC3=CC=C(C=C3)F)OC
MDL Number:
MFCD00869327
Purity :
98%
Available in stock:
168.056 g

More details are to be found here