BGC > Product Search > OSU-03012 | 742112-33-0

Molecular Formula: C26H19F3N4O
Molecular Weight: 460.46

Molecular Formula: C26H19F3N4O
Molecular Weight: 460.46

Description :
OSU 03012 is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. OSU 03012 may also cause cell death through the induction of stress in the endoplasmic reticulum.

• Molecular Weight :460.46
• Purity :> 98%

Molecular Formula :
C26H19F3N4O
Canonical SMILES :
C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
InChI :
InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
InChIKey :
YULUCECVQOCQFQ-UHFFFAOYSA-N
Appearance :
Solid Powder
Synonyms :
AR-12; OSU-03012; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide

More details are to be found here

Description :
OSU 03012 is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. OSU 03012 may also cause cell death through the induction of stress in the endoplasmic reticulum.

• Molecular Weight :460.46
• Purity :> 98%

Molecular Formula :
C26H19F3N4O
Canonical SMILES :
C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
InChI :
InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
InChIKey :
YULUCECVQOCQFQ-UHFFFAOYSA-N
Appearance :
Solid Powder
Synonyms :
AR-12; OSU-03012; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide

More details are to be found here

Description :
OSU 03012 is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. OSU 03012 may also cause cell death through the induction of stress in the endoplasmic reticulum.

• Molecular Weight :460.46
• Purity :> 98%

Molecular Formula :
C26H19F3N4O
Canonical SMILES :
C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
InChI :
InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
InChIKey :
YULUCECVQOCQFQ-UHFFFAOYSA-N
Appearance :
Solid Powder
Synonyms :
AR-12; OSU-03012; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide

More details are to be found here