BGC > Product Search > UNC-0638 | 1255580-76-7

Molecular Formula: C30H47N5O2
Molecular Weight: 509.72648

Molecular Formula: C30H47N5O2
Molecular Weight: 509.72648

Molecular Formula: C30H47N5O2
Molecular Weight: 509.72648

Description :
UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity. UNC0638 markedly reduced the clonogenicity of MCF7 cells, reduced the abundance of H3K9me2 marks at promoters of known G9a-regulated endogenous genes and disproportionately affected several genomic loci encoding microRNAs.

• Molecular Weight :509.739
• Boiling Point :563.9±50.0 °C at 760 mmHg
• Melting Point :93-94 ºC
• Purity :0.98

Molecular Formula :
C30H47N5O2
Canonical SMILES :
CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
InChI :
InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33)
InChIKey :
QOECJCJVIMVJGX-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : ≥ 30 mg/mL (58.85 mM)
Appearance :
white solid powder
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
UNC0638, UNC-0638, UNC 0638

More details are to be found here