BGC > Product Search > 2-[1-Benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic aci d | 393105-53-8

Molecular Formula: C24H16F3NO4

Molecular Formula: C24H16F3NO4

Molecular Formula: C24H16F3NO4

Molecular Formula: C24H16F3NO4

Description :
Tiplaxtinin is a novel plasminogen activator inhibitor-1 (PAI-1) inhibitor. It is an orally active prothrombolytic drug that inhibits PAI-1 and accelerates fibrinolysis while maintaining normal coagulation in a model of coronary occlusion. It exerts antithrombotic efficacy in rat models of arterial and venous vascular injury without effecting platelet aggregation.

• Molecular Weight :439.38
• Purity :> 98%

Molecular Formula :
C24H16F3NO4
Canonical SMILES :
C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O
InChI :
InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
InChIKey :
ODXQFEWQSHNQNI-UHFFFAOYSA-N
Synonyms :
Tiplaxtinin; PAI039; PAI-039; PAI 039.

More details are to be found here

Description :
Tiplaxtinin is a novel plasminogen activator inhibitor-1 (PAI-1) inhibitor. It is an orally active prothrombolytic drug that inhibits PAI-1 and accelerates fibrinolysis while maintaining normal coagulation in a model of coronary occlusion. It exerts antithrombotic efficacy in rat models of arterial and venous vascular injury without effecting platelet aggregation.

• Molecular Weight :439.38
• Purity :> 98%

Molecular Formula :
C24H16F3NO4
Canonical SMILES :
C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O
InChI :
InChI=1S/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
InChIKey :
ODXQFEWQSHNQNI-UHFFFAOYSA-N
Synonyms :
Tiplaxtinin; PAI039; PAI-039; PAI 039.

More details are to be found here