BGC > Product Search > Lys05

Description :
Lys05, a water-soluble salt of Lys01, is a selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively, resulting in sustained inhibition of autophagy and tumor growth.

• Molecular Weight :549.75

Molecular Formula :
C23H26Cl5N5
Canonical SMILES :
CN(CCNC1=C2C=CC(=CC2=NC=C1)Cl)CCNC3=C4C=CC(=CC4=NC=C3)Cl.Cl.Cl.Cl
InChI :
InChI=1S/C23H23Cl2N5.3ClH/c1-30(12-10-28-20-6-8-26-22-14-16(24)2-4-18(20)22)13-11-29-21-7-9-27-23-15-17(25)3-5-19(21)23;;;/h2-9,14-15H,10-13H2,1H3,(H,26,28)(H,27,29);3*1H
InChIKey :
JTUYDBHQGOZPQQ-UHFFFAOYSA-N
Solubility :
Soluble to 6.4 mg/mL in water.
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
LYS-05 HCl; LYS05; LYS-05; Lys01 trihydrochloride; Lys01 3HCl; N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine trihydrochloride

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