BGC > Product Search > Nutlin-3 | 548472-68-0

Molecular Formula: C30H30Cl2N4O4
Molecular Weight: 581.49
Hazard Symbols: Xi
WGKGermany: 3

Description :
Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 µM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches.

• Molecular Weight :581.49
• Purity :> 98%

Molecular Formula :
C30H30Cl2N4O4
Canonical SMILES :
CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
InChI :
InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)
InChIKey :
BDUHCSBCVGXTJM-UHFFFAOYSA-N
Solubility :
Soluble in DMSO.
Appearance :
White Solid
Storage : Store at -20°C
Synonyms :
(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one

More details are to be found here

Smile code:
O=C1NCCN(C(N2[C@@H](C3=CC=C(Cl)C=C3)[C@@H](C4=CC=C(Cl)C=C4)N=C2C5=CC=C(OC)C=C5OC(C)C)=O)C1
MDL Number:
MFCD07784509
Purity :
98%
Available in stock:
12.412 g

More details are to be found here

Formula:
C30H30Cl2N4O4
Mol Weight:
581,49g/mol

Formula:
C30H30Cl2N4O4
Mol Weight:
581,49g/mol

Formula:
C30H30Cl2N4O4
Mol Weight:
581,49g/mol