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Suppliers for CAS
229971-81-7
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Properties | | CAS |
229971-81-7 |
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4 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C22H34N8O6S2
Molecular Weight: 570.68536
Phcoker
P.R.China
Molecular Formula: C22H34N8O6S2
Molecular Weight: 570.68536
BOC Sciences
USA
Description : Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. - Molecular Weight :570.69
- Boiling Point :1183.4±65.0°C at 760 mmHg
- Purity :98%
Molecular Formula : C22H34N8O6S2 Canonical SMILES : CC1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CN=CN2)NC(=O)C)C(=O)N)C(C)C
InChI :
InChI=1S/C22H34N8O6S2/c1-10(2)17-22(36)29-15(18(23)32)7-37-38-8-16(27-12(4)31)21(35)28-14(5-13-6-24-9-25-13)20(34)26-11(3)19(33)30-17/h6,9-11,14-17H,5,7-8H2,1-4H3,(H2,23,32)(H,24,25)(H,26,34)(H,27,31)(H,28,35)(H,29,36)(H,30,33)/t11-,14-,15-,16-,17-/m0/s1
InChIKey :
FQVLRGLGWNWPSS-BXBUPLCLSA-N
Solubility :
Soluble in DMSO
Appearance :
white solid powder
Storage : Store at -20°C
Synonyms :
NSC729477; ADH-1; NSC7 29477; ADH 1; NSC-729477; ADH1
More details are to be found here
Alpha Biopharmaceuticals Co., Ltd.
P.R.China
Description : Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. - Molecular Weight :570.69
- Boiling Point :1183.4±65.0°C at 760 mmHg
- Purity :98%
Molecular Formula : C22H34N8O6S2 Canonical SMILES : CC1C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CN=CN2)NC(=O)C)C(=O)N)C(C)C
InChI :
InChI=1S/C22H34N8O6S2/c1-10(2)17-22(36)29-15(18(23)32)7-37-38-8-16(27-12(4)31)21(35)28-14(5-13-6-24-9-25-13)20(34)26-11(3)19(33)30-17/h6,9-11,14-17H,5,7-8H2,1-4H3,(H2,23,32)(H,24,25)(H,26,34)(H,27,31)(H,28,35)(H,29,36)(H,30,33)/t11-,14-,15-,16-,17-/m0/s1
InChIKey :
FQVLRGLGWNWPSS-BXBUPLCLSA-N
Solubility :
Soluble in DMSO
Appearance :
white solid powder
Storage : Store at -20°C
Synonyms :
NSC729477; ADH-1; NSC7 29477; ADH 1; NSC-729477; ADH1
More details are to be found here
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Exherin |
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