Description :
ODM-201 is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR.
- Molecular Weight :389.85
- Purity :98%
Molecular Formula :
C19H19ClN6O2
Canonical SMILES :
O=C(C1=NNC(C(O)C)=C1)N[C@@H](C)CN2N=C(C3=CC=C(C#N)C(Cl)=C3)C=C2
Solubility :
Soluble in DMSO, not in water
Appearance :
Solid powder
Storage : Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms :
ODM-201; ODM 201; ODM201.
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