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Suppliers for CAS
1032900-25-6
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Properties | | CAS |
1032900-25-6 | | Formula |
C28H36ClN5O3S |
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11 Registered suppliers
Amadis Chemical Company Limited
P.R.China
H&Z Industry Co.,Ltd
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Capot Chemical Co., Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Chemvon Biotechnology Co. Ltd.
P.R.China
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Aea.ltd
P.R.China
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Molecular Formula: C28H36ClN5O3S
Molecular Weight: 558.13514
Finetech Industry Limited
P.R.China
More details are to be found here
BOC Sciences
USA
Description : An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. - Molecular Weight :558.14
- Purity :≥98%
Molecular Formula : C28H36ClN5O3S Canonical SMILES : CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl
InChI :
InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)
InChIKey :
VERWOWGGCGHDQE-UHFFFAOYSA-N
Solubility :
Soluble in DMSO.
Appearance :
Solid Powder
Application :
Antineoplastic Agents
Storage : Store at -20ēC
Synonyms :
5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX
More details are to be found here
Shandong SanYoung Industry Co., Ltd
P.R.China
Description : An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. - Molecular Weight :558.14
- Purity :≥98%
Molecular Formula : C28H36ClN5O3S Canonical SMILES : CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl
InChI :
InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)
InChIKey :
VERWOWGGCGHDQE-UHFFFAOYSA-N
Solubility :
Soluble in DMSO.
Appearance :
Solid Powder
Application :
Antineoplastic Agents
Storage : Store at -20ēC
Synonyms :
5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX
More details are to be found here
Chemos GmbH & Co. KG
Germany
Description : An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. - Molecular Weight :558.14
- Purity :≥98%
Molecular Formula : C28H36ClN5O3S Canonical SMILES : CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl
InChI :
InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)
InChIKey :
VERWOWGGCGHDQE-UHFFFAOYSA-N
Solubility :
Soluble in DMSO.
Appearance :
Solid Powder
Application :
Antineoplastic Agents
Storage : Store at -20ēC
Synonyms :
5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX
More details are to be found here
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