BGC > Product Search > 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile | 252917-06-9

Molecular Formula: C22H18Cl2N8
Molecular Weight: 465.35
Hazard Symbols: T
UN Number: UN 2811 6.1 / PGIII
WGKGermany: 3
HS Code: 29335990

Molecular Formula: C22H18Cl2N8
Molecular Weight: 465.34

Molecular Formula: C22H18Cl2N8
Molecular Weight: 465.34

Molecular Formula: C22H18Cl2N8
Molecular Weight: 465.34

Molecular Formula: C22H18Cl2N8
Molecular Weight: 465.34

Description :
CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES).

• Molecular Weight :465.342
• Purity :> 98%

Molecular Formula :
C22H18Cl2N8
Canonical SMILES :
CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N
InChI :
InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
InChIKey :
AQGNHMOJWBZFQQ-UHFFFAOYSA-N
Appearance :
Solid Powder
Application :
potential antineoplastic agent
Synonyms :
CHIR-99021; CT99021; 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile

More details are to be found here

Purity : 98%
Smile code : N#CC1=CN=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1
MDL Number : MFCD11846251
MolFormula : C22H18Cl2N8
MolWeight : 465.3379
Available in stock : 1.939

More details are to be found here

Smile code:
N#CC1=CN=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1
MDL Number:
MFCD11846251
Purity :
98%
Available in stock:
11.707 g

More details are to be found here

Smile code:
N#CC1=CN=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1
MDL Number:
MFCD11846251
Purity :
98%
Available in stock:
11.707 g

More details are to be found here

Smile code:
N#CC1=CN=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1
MDL Number:
MFCD11846251
Purity :
98%
Available in stock:
11.707 g

More details are to be found here

Smile code:
N#CC1=CN=C(NCCNC2=NC=C(C3=NC=C(C)N3)C(C4=CC=C(Cl)C=C4Cl)=N2)C=C1
MDL Number:
MFCD11846251
Purity :
98%
Available in stock:
11.707 g

More details are to be found here