BGC > Product Search > UNC 1999 | 1431612-23-5

Molecular Formula: C33H43N7O2
Molecular Weight: 569.74022
Hazard Symbols: Xn
WGKGermany: 3

Molecular Formula: C33H43N7O2
Molecular Weight: 569.74022
Hazard Symbols: Xn
WGKGermany: 3

Description :
UNC1999, the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. UNC1999 was highly selective for EZH2 and EZH1 over a broad range of epigenetic and non-epigenetic targets. UNC1999 was orally bioavailable in mice, making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies. UNC-1999 represents a useful tools for the biomedical community to investigate the role of EZH2 and EZH1 in health and disease.

• Molecular Weight :569.754
• Purity :0.98

Molecular Formula :
C33H43N7O2
Canonical SMILES :
CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(C)C)C(C)C
InChI :
InChI=1S/C33H43N7O2/c1-7-8-24-15-23(6)37-33(42)28(24)19-35-32(41)27-16-26(17-30-29(27)20-36-40(30)22(4)5)25-9-10-31(34-18-25)39-13-11-38(12-14-39)21(2)3/h9-10,15-18,20-22H,7-8,11-14,19H2,1-6H3,(H,35,41)(H,37,42)
InChIKey :
DPJNKUOXBZSZAI-UHFFFAOYSA-N
Appearance :
white solid powder
Synonyms :
UNC1999; UNC 1999; UNC-1999;

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