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BGC > Product Search > RTA402 | 218600-53-4
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Suppliers for CAS

218600-53-4


Properties

CAS   218600-53-4 
Formula   C32H43NO4 

8 Registered suppliers


Amadis Chemical Company Limited P.R.China
Dayang Chem (Hangzhou) Co.,Ltd. P.R.China

More details are to be found here
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C32H43NO4
Molecular Weight: 505.68812
Finetech Industry Limited P.R.China
Hangzhou Lingrui Chemical Co., Ltd. P.R.China

More details are to be found here
BOC Sciences USA
CM Fine Chemicals Switzerland
Description :
Bardoxolone methyl (also known as ´RTA 402´ and ´CDDO-methyl ester´) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation.
  • Molecular Weight :505.70
  • Boiling Point :600.8ºC at 760 mmHg
  • Purity :≥ 98.0%
Molecular Formula :
C32H43NO4
Canonical SMILES :
CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)OC)C
InChI :
InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-31(7)24(20(32)17-27)21(34)15-23-29(5)16-19(18-33)25(35)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3/t20-,22-,24?,29-,30+,31+,32-/m0/s1
InChIKey :
WPTTVJLTNAWYAO-FUARBKCBSA-N
Solubility :
Soluble in DMSO, not in water
Appearance :
Off-white to yellow powder
Application :
A Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells; Antioxidant inflammation modulator (AIM); For the treatment of advanced chronic kidney disease (CKD) in type 2 diabetes mellitus patients
Storage : Store in dry, dark and ventilated place.
Synonyms :
CDDO Methyl ester; CDDOMe; RTA 402; RTA-402; RTA402; TP-155; TP155; TP 155; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid methyl ester; bardoxolone methyl; CDDO-Me; methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate; (4aS,6aR,6bS,8aR,12aS,14bS)-Methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylate
More details are to be found here

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Properties:

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