BGC > Product Search > SPHINX31 | 1818389-84-2

Molecular Formula: C27H24F3N5O2
Molecular Weight: 507.507

Molecular Formula: C27H24F3N5O2
Molecular Weight: 507.507

Description :
SPHINX31 is a potent and selective inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) (IC50 value of 6 nM). It inhibits SRPK1 activity and phosphorylation of serine/arginine splicing factor 1 (SRSF1), increasing expression of the anti-angiogenic VEGF-A165b splice variant in retinal pigment epithelial (RPE) cells.

• Molecular Weight :507.51
• Purity :99%

Molecular Formula :
C27H24F3N5O2
Canonical SMILES :
C1CN(CCN1CC2=CC=CC=N2)C3=C(C=C(C=C3)C(F)(F)F)NC(=O)C4=CC=C(O4)C5=CC=NC=C5
InChI :
InChI=1S/C27H24F3N5O2/c28-27(29,30)20-4-5-23(35-15-13-34(14-16-35)18-21-3-1-2-10-32-21)22(17-20)33-26(36)25-7-6-24(37-25)19-8-11-31-12-9-19/h1-12,17H,13-16,18H2,(H,33,36)
InChIKey :
VURLRACCOCGFDB-UHFFFAOYSA-N
Synonyms :
SPHINX31; SPHINX-31; SPHINX 31; 5-(4-pyridinyl)-N-[2-[4-(2-pyridinylmethyl)-1-piperazinyl]-5-(trifluoromethyl)phenyl]-2-furancarboxamide

More details are to be found here