BGC > Product Search > 4-(Pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one | 1443211-72-0

Description :
Eleclazine is a selective Sodium channel antagonist. Eleclazin showed a shortening of the QTc interval (the time interval between the start of the Q-wave and end of the T-wave in the heart's electrical cycle) in patients with long QT-3 (LQT3) syndrome. Phase III clinical trilas for the treatment of Long QT syndrome, Phase II/III clinical trilas for the treatment of Hypertrophic cardiomyopathy and Phase II clinical trilas for the treatment of Ventricular arrhythmias are on-going.

• Molecular Weight :415.37
• Purity :98%

Molecular Formula :
C21H16F3N3O3
Canonical SMILES :
c1cnc(nc1)CN2CCOc3ccc(cc3C2=O)c4ccc(cc4)OC(F)(F)F
InChI :
1S/C21H16F3N3O3/c22-21(23,24)30-16-5-2-14(3-6-16)15-4-7-18-17(12-15)20(28)27(10-11-29-18)13-19-25-8-1-9-26-19/h1-9,12H,10-11,13H2
InChIKey :
YNUAEEJQYHYLMS-UHFFFAOYSA-N
Solubility :
Soluble in DMSO
Appearance :
Powder
Application :
Long QT syndrome;Hypertrophic cardiomyopathy;Ventricular arrhythmias
Storage : -20°C Freezer
Synonyms :
GS-6615; GS 6615; GS6615; Eleclazine. 4-[(pyrimidin-2-yl)methyl]-7-[4-(trifluoromethoxy)phenyl]- 3,4-dihydro-1,4-benzoxazepin-5(2H)-one

More details are to be found here

Purity : 95%
Smile code : O=C1N(CC2=NC=CC=N2)CCOC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C13
MDL Number : MFCD28963966
MolFormula : C21H16F3N3O3
MolWeight : 415.3653
Available in stock : 0.25

More details are to be found here