BGC > Product Search > Apremilast

Molecular Formula: C19H20N2O6S
Molecular Weight: 404.4369

Purity: 99%

Purity: 99%

Purity: 99%

Purity: 99%

Purity: 99%

Purity: 99%

Purity: 99%

Purity: 99%

Description :
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells.

• Molecular Weight :460.50
• Boiling Point :741.3±60.0°C (Predicted)
• Melting Point :154-156 °C
• Purity :> 98%

Molecular Formula :
C22H24N2O7S
Canonical SMILES :
CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
InChI :
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey :
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
Solubility :
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
Appearance :
Off-White to Pale Yellow Solid
Application :
Anti-inflammatory agents, Non-steroidal; phosphodiesterase inhibitors
Storage : Store at 2-8°C
Synonyms :
(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004

More details are to be found here

Description :
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells.

• Molecular Weight :460.50
• Boiling Point :741.3±60.0°C (Predicted)
• Melting Point :154-156 °C
• Purity :> 98%

Molecular Formula :
C22H24N2O7S
Canonical SMILES :
CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
InChI :
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey :
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
Solubility :
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
Appearance :
Off-White to Pale Yellow Solid
Application :
Anti-inflammatory agents, Non-steroidal; phosphodiesterase inhibitors
Storage : Store at 2-8°C
Synonyms :
(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004

More details are to be found here

Description :
Apremilast is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells.

• Molecular Weight :460.50
• Boiling Point :741.3±60.0°C (Predicted)
• Melting Point :154-156 °C
• Purity :> 98%

Molecular Formula :
C22H24N2O7S
Canonical SMILES :
CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
InChI :
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey :
IMOZEMNVLZVGJZ-QGZVFWFLSA-N
Solubility :
Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
Appearance :
Off-White to Pale Yellow Solid
Application :
Anti-inflammatory agents, Non-steroidal; phosphodiesterase inhibitors
Storage : Store at 2-8°C
Synonyms :
(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004; CC10004; CC-10004

More details are to be found here