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Suppliers for CAS
918633-87-1
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Properties | | CAS |
918633-87-1 | | Formula |
C9H16Br2N5O4P |
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6 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C9H16Br2N5O4P
Molecular Weight: 449.036201
Aea.ltd
P.R.China
Molecular Formula: C9H16Br2N5O4P
Molecular Weight: 449.036201
BOC Sciences
USA
Description : Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. - Molecular Weight :449.04
- Melting Point :97-98°C
- Purity :> 98%
Molecular Formula : C9H16Br2N5O4P Canonical SMILES : CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr InChI : InChI=1S/C9H16Br2N5O4P/c1-15-8(6-12-9(15)16(17)18)7-20-21(19,13-4-2-10)14-5-3-11/h6H,2-5,7H2,1H3,(H2,13,14,19)
InChIKey :
UGJWRPJDTDGERK-UHFFFAOYSA-N
Appearance :
Off-White to Pale Yellow Solid
Synonyms :
TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine
More details are to be found here
Santa Cruz Biotechnology, Inc.
USA
Description : Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. - Molecular Weight :449.04
- Melting Point :97-98°C
- Purity :> 98%
Molecular Formula : C9H16Br2N5O4P Canonical SMILES : CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr InChI : InChI=1S/C9H16Br2N5O4P/c1-15-8(6-12-9(15)16(17)18)7-20-21(19,13-4-2-10)14-5-3-11/h6H,2-5,7H2,1H3,(H2,13,14,19)
InChIKey :
UGJWRPJDTDGERK-UHFFFAOYSA-N
Appearance :
Off-White to Pale Yellow Solid
Synonyms :
TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine
More details are to be found here
Detailed information on the suppliers of
TH-302 |
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