BGC > Product Search > Tp-064 | 2080306-20-1

Molecular Formula: C28H34N4O2
Molecular Weight: 458.59516

Description :
TP 064 is a potent and selective PRMT4 inhibitor with > 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits methylation of H3 (1-25) and MED12 in cellular assays (IC50 values are <10 and 43 nM, respectively).

• Molecular Weight :458.6
• Boiling Point :642.8±55.0 °C at 760 mmHg
• Purity :≥98% by HPLC

Molecular Formula :
C28H34N4O2
Canonical SMILES :
CNCCN1CCC(CC1)C2=NC=CC(=C2)CN(C)C(=O)C3=CC(=CC=C3)OC4=CC=CC=C4
InChI :
InChI=1S/C28H34N4O2/c1-29-15-18-32-16-12-23(13-17-32)27-19-22(11-14-30-27)21-31(2)28(33)24-7-6-10-26(20-24)34-25-8-4-3-5-9-25/h3-11,14,19-20,23,29H,12-13,15-18,21H2,1-2H3
InChIKey :
VUIITYLFSAXKIQ-UHFFFAOYSA-N
Synonyms :
TP-064; TP064; N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide

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