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Suppliers for
Sacubitril
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Properties | CAS |
149709-62-6 | Formula |
C24H29NO5 |
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2 Registered suppliers
Description : Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. - Molecular Weight :411.49
- Purity :> 98%
Molecular Formula : C24H29NO5 Canonical SMILES : CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O InChI : InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m1/s1 InChIKey : PYNXFZCZUAOOQC-UTKZUKDTSA-N Appearance : Light yellow oil Synonyms : Sacubitril; AHU 377; AHU377
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Sacubitril
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Last update 2024-05-06
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