BGC > Product Search > 5-(5-Methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole | 1570496-34-2

Molecular Formula: C25H25F3N6O4S
Molecular Weight: 562.5640096

Molecular Formula: C25H25F3N6O4S
Molecular Weight: 562.5640096

Description :
IACS-010759 is an orally bioavailable inhibitor of mitochondrial oxidative phosphorylation (OXPHOS), targeting complex I of the electron transport chain (NADH ubiquinone oxidoreductase). Study showed that IACS-010759 induced AMPK activation leading to mTOR suppression which resulted in cell growth inhibition in AML cells.

• Molecular Weight :562.57
• Boiling Point :768.0±70.0 °C at 760 mmHg
• Purity :≥98%

Molecular Formula :
C25H25F3N6O4S
Canonical SMILES :
CC1=NC(=NN1CC2=CC(=CC=C2)N3CCC(CC3)S(=O)(=O)C)C4=NC(=NO4)C5=CC=C(C=C5)OC(F)(F)F
InChI :
InChI=1S/C25H25F3N6O4S/c1-16-29-23(24-30-22(32-38-24)18-6-8-20(9-7-18)37-25(26,27)28)31-34(16)15-17-4-3-5-19(14-17)33-12-10-21(11-13-33)39(2,35)36/h3-9,14,21H,10-13,15H2,1-2H3
InChIKey :
HWJWNWZJUYCGKV-UHFFFAOYSA-N
Appearance :
Crystalline Solid
Synonyms :
5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole

More details are to be found here