BGC > Product Search > (3'R)-Ezetimibe

Molecular Formula: C24H21F2NO3
Molecular Weight: 409.4252464

Description :
Azetidinone Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.

• Molecular Weight :409.44
• Melting Point :124-126 °C
• Purity :> 95%

Molecular Formula :
C24H21F2NO3
Canonical SMILES :
C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
InChI :
InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22-,23-/m1/s1
InChIKey :
OLNTVTPDXPETLC-DNVJHFABSA-N
Appearance :
White Solid
Synonyms :
(3'R)-Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone;

More details are to be found here

Description :
Azetidinone Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes.

• Molecular Weight :409.44
• Melting Point :124-126 °C
• Purity :> 95%

Molecular Formula :
C24H21F2NO3
Canonical SMILES :
C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
InChI :
InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22-,23-/m1/s1
InChIKey :
OLNTVTPDXPETLC-DNVJHFABSA-N
Appearance :
White Solid
Synonyms :
(3'R)-Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone;

More details are to be found here