BGC > Product Search > SU5408 | 15966-93-5

Molecular Formula: C18H18N2O3
Molecular Weight: 310.34712

Description :
A potent, selective and cell-permeable inhibitor of VEGFR2 kinase(IC50= 70 nM) with little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 µM).

• Molecular Weight :310.35
• Boiling Point :571.4±50.0 ℃ at 760 Torr

Molecular Formula :
C18H18N2O3
Canonical SMILES :
CCOC(=O)C1=C(NC(=C1C)C=C2C3=CC=CC=C3NC2=O)C
InChI :
1S/C18H18N2O3/c1-4-23-18(22)16-10(2)15(19-11(16)3)9-13-12-7-5-6-8-14(12)20-17(13)21/h5-9,19H,4H2,1-3H3,(H,20,21)
InChIKey :
PMUJUSJUVIXDQC-UHFFFAOYSA-N
Solubility :
DMSO: 6 mg/mL
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
SU-5408; SU 5408; SU5408; ethyl 2,4-dimethyl-5-[(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate; VEGFR2 Kinase Inhibitor I; IN1018

More details are to be found here

Description :
A potent, selective and cell-permeable inhibitor of VEGFR2 kinase(IC50= 70 nM) with little or no effect against receptors for platelet-derived growth factor, epidermal growth factor, or insulin-like growth factor (IC50 > 100 µM).

• Molecular Weight :310.35
• Boiling Point :571.4±50.0 ℃ at 760 Torr

Molecular Formula :
C18H18N2O3
Canonical SMILES :
CCOC(=O)C1=C(NC(=C1C)C=C2C3=CC=CC=C3NC2=O)C
InChI :
1S/C18H18N2O3/c1-4-23-18(22)16-10(2)15(19-11(16)3)9-13-12-7-5-6-8-14(12)20-17(13)21/h5-9,19H,4H2,1-3H3,(H,20,21)
InChIKey :
PMUJUSJUVIXDQC-UHFFFAOYSA-N
Solubility :
DMSO: 6 mg/mL
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
SU-5408; SU 5408; SU5408; ethyl 2,4-dimethyl-5-[(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate; VEGFR2 Kinase Inhibitor I; IN1018

More details are to be found here