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BGC > Product Search > Selumetinib | 606143-52-6
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Suppliers for CAS

606143-52-6


Properties

CAS   606143-52-6 
Formula   C17H15BrClFN4O3 

Structure

12 Registered suppliers


U-Chemo Scientific (Shanghai) Co.,Ltd. P.R.China
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Shandong Ench Chemical Co.,Ltd P.R.China
Aea.ltd P.R.China
Appearance   Beige powder.
Purity   99% min

Appearance   Beige powder.
Purity   99% min

Hangzhou Zhongqi Chem Co., Ltd P.R.China
Appearance   Beige powder.
Purity   99% min

Finetech Industry Limited P.R.China
BOC Sciences USA
AK Scientific, Inc. USA
Description :
Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent.
  • Molecular Weight :457.684
  • Purity :> 98%
Molecular Formula :
C17H15BrClFN4O3
Canonical SMILES :
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
InChI :
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChIKey :
CYOHGALHFOKKQC-UHFFFAOYSA-N
Appearance :
white solid powder
Storage : Powder stores in -20ēC directly, which is effective for a period of 2 years.
Synonyms :
ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886
More details are to be found here
Chemtour Biotech Co., Ltd P.R.China
Description :
Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent.
  • Molecular Weight :457.684
  • Purity :> 98%
Molecular Formula :
C17H15BrClFN4O3
Canonical SMILES :
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
InChI :
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChIKey :
CYOHGALHFOKKQC-UHFFFAOYSA-N
Appearance :
white solid powder
Storage : Powder stores in -20ēC directly, which is effective for a period of 2 years.
Synonyms :
ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886
More details are to be found here
CM Fine Chemicals Switzerland
Description :
Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent.
  • Molecular Weight :457.684
  • Purity :> 98%
Molecular Formula :
C17H15BrClFN4O3
Canonical SMILES :
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
InChI :
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChIKey :
CYOHGALHFOKKQC-UHFFFAOYSA-N
Appearance :
white solid powder
Storage : Powder stores in -20ēC directly, which is effective for a period of 2 years.
Synonyms :
ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886
More details are to be found here
Santa Cruz Biotechnology, Inc. USA
Description :
Selumetinib, also known as AZD6244, is an orally bioavailable small molecule with potential antineoplastic activity. Selumetinib inhibits mitogen-activated protein kinase kinases (MEK or MAPK/ERK kinases) 1 and 2, which may prevent the activation of MEK1/2-dependent effector proteins and transcription factors, and so may inhibit cellular proliferation in MEK-overexpressing tumor cells. MEK 1 and 2 are dual-specificity kinases that are essential mediators in the activation of the RAS/RAF/MEK/ERK pathway, are often upregulated in various tumor cell types, and are drivers of diverse cellular activities, including cellular proliferation. Check for active clinical trials or closed clinical trials using this agent.
  • Molecular Weight :457.684
  • Purity :> 98%
Molecular Formula :
C17H15BrClFN4O3
Canonical SMILES :
CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
InChI :
InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
InChIKey :
CYOHGALHFOKKQC-UHFFFAOYSA-N
Appearance :
white solid powder
Storage : Powder stores in -20ēC directly, which is effective for a period of 2 years.
Synonyms :
ARRY-142886; ARRY 142886; ARRY142886; AZD6244; AZD-6244; AZD 6244; ARRY-886; ARRY886; ARRY 886
More details are to be found here

Detailed information on the suppliers of Selumetinib

Properties:

... more properties and specification on Selumetinib
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