BGC > Product Search > Disodium methotrexate | 7413-34-5

Molecular Formula: C20H20N8Na2O5
Molecular Weight: 498.4

Molecular Formula: C20H20N8Na2O5
Molecular Weight: 498.41

Molecular Formula: C20H20N8Na2O5
Molecular Weight: 498.41

Molecular Formula: C20H20N8Na2O5
Molecular Weight: 498.41

Description :
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

• Molecular Weight :498.40
• Boiling Point :823℃
• Melting Point :> 255°C (dec.)
• Purity :> 98.0%

Molecular Formula :
C20H20N8Na2O5
Canonical SMILES :
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
InChI :
InChI=1S/C20H22N8O5.2Na/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);;/q;2*+1/p-2/t13-;;/m0../s1
InChIKey :
DASQOOZCTWOQPA-GXKRWWSZSA-L
Solubility :
10 mm in DMSO
Appearance :
Yellow Solid
Storage : Store at -5°C,keep in dry and avoid sunlight.
Synonyms :
Amethopterin Sodium; Methotrexate Lederle; Metoart; Metotrexato Lederle; Sodium Methotrexate; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Disodium Salt; 4-amino-n(sup10)-methyl pteroyl glutamic acid disodium salt; amethopterin sodium

More details are to be found here

Description :
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).

• Molecular Weight :498.40
• Boiling Point :823℃
• Melting Point :> 255°C (dec.)
• Purity :> 98.0%

Molecular Formula :
C20H20N8Na2O5
Canonical SMILES :
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
InChI :
InChI=1S/C20H22N8O5.2Na/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);;/q;2*+1/p-2/t13-;;/m0../s1
InChIKey :
DASQOOZCTWOQPA-GXKRWWSZSA-L
Solubility :
10 mm in DMSO
Appearance :
Yellow Solid
Storage : Store at -5°C,keep in dry and avoid sunlight.
Synonyms :
Amethopterin Sodium; Methotrexate Lederle; Metoart; Metotrexato Lederle; Sodium Methotrexate; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Disodium Salt; 4-amino-n(sup10)-methyl pteroyl glutamic acid disodium salt; amethopterin sodium

More details are to be found here

MF: C20H20N8Na2O5
MW: 498,40

Smile code:
O=C([O-])[C@@H](NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O)CCC([O-])=O.[Na+].[Na+]
MDL Number:
MFCD00274560
Purity :
98%
Available in stock:
75 g

More details are to be found here

Smile code:
O=C([O-])[C@@H](NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O)CCC([O-])=O.[Na+].[Na+]
MDL Number:
MFCD00274560
Purity :
98%
Available in stock:
75 g

More details are to be found here

Smile code:
O=C([O-])[C@@H](NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O)CCC([O-])=O.[Na+].[Na+]
MDL Number:
MFCD00274560
Purity :
98%
Available in stock:
75 g

More details are to be found here