BGC > Product Search > Entrectinib | 1108743-60-7

Molecular Formula: C31H34F2N6O2

Molecular Formula: C31H34F2N6O2

Description :
Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Phase 2.

• Molecular Weight :560.64
• Purity :≥98%

Molecular Formula :
C31H34F2N6O2
Canonical SMILES :
CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6
InChI :
InChI=1S/C31H34F2N6O2/c1-38-8-10-39(11-9-38)25-3-4-26(29(19-25)34-24-6-12-41-13-7-24)31(40)35-30-27-17-20(2-5-28(27)36-37-30)14-21-15-22(32)18-23(33)16-21/h2-5,15-19,24,34H,6-14H2,1H3,(H2,35,36,37,40)
InChIKey :
HAYYBYPASCDWEQ-UHFFFAOYSA-N
Appearance :
Solid Powder
Application :
Protein Kinase Inhibitors
Synonyms :
RXDX101; RXDX 101; RXDX-101; NMS E628; NMS-E628; Entrectinib; N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide

More details are to be found here

MF: C31H34F2N6O2
MW: 560,64

MF: C31H34F2N6O2
MW: 560,64