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BGC > Product Search > AZ-960 | 905586-69-8
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Suppliers for CAS

905586-69-8



 

Properties

CAS   905586-69-8 
Formula   C18H16F2N6 

4 Registered suppliers


Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C18H16F2N6
Molecular Weight: 354.36
BOC Sciences USA
Santa Cruz Biotechnology, Inc. USA
Description :
AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM.
  • Molecular Weight :354.36
  • Boiling Point :515.2±50.0°C (Predicted)
  • Purity :> 98%
Molecular Formula :
C18H16F2N6
Canonical SMILES :
CC1=CC(=NN1)NC2=C(C=C(C(=N2)NC(C)C3=CC=C(C=C3)F)C#N)F
InChI :
InChI=1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1
InChIKey :
SUNXHXDJOIXABJ-NSHDSACASA-N
Solubility :
Soluble in DMSO
Appearance :
Light Yellow to Yellow Solid
Storage : Store at 2-8°C
Synonyms :
(S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; 3-Pyridinecarbonitrile, 5-fluoro-2-(((1S)-1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)-; 5-Fluoro-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]nicotinonitrile
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