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BGC > Product Search > XL-147 | 956958-53-5
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Suppliers for CAS

956958-53-5



 

Properties

CAS   956958-53-5 
Formula   C21H16N6O2S2 

7 Registered suppliers


Amadis Chemical Company Limited P.R.China
Hangzhou Keying Chem Co., Ltd. P.R.China

More details are to be found here
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C21H16N6O2S2
Molecular Weight: 448.52074
BOC Sciences USA
Santa Cruz Biotechnology, Inc. USA
Description :
Pilaralisib is a Class 1 phosphatidylinositol 3 kinase (PI3K) family inhibitor. It is an orally bioavailable small molecule, targeting the class I PI3K family of lipid kinases. It is a pyrimidine derivatives compound discovered by Exelixis Inc. It has potential antineoplastic activity. It binds to class 1 PI3Ks in an ATP-competitive manner by inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and inhibiting the activation of the PI3K signaling pathway.
  • Molecular Weight :448.52
  • Boiling Point :638.9±65.0 °C | Condition: Press: 760 Torr
  • Purity :> 99%
Molecular Formula :
C21H16N6O2S2
Canonical SMILES :
CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4
InChI :
InChI=1S/C21H16N6O2S2/c1-13-6-9-15(10-7-13)31(28,29)27-21-20(23-16-4-2-3-5-17(16)24-21)22-14-8-11-18-19(12-14)26-30-25-18/h2-12H,1H3,(H,22,23)(H,24,27)
InChIKey :
MQMKRQLTIWPEDM-UHFFFAOYSA-N
Solubility :
DMSO ≥86mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL
Appearance :
White to off-white Solid
Application :
Pilaralisib has potential antineoplastic activity.
Storage : -20°C Freezer
Synonyms :
XL147-II; XL147 II; XL147II; XL147 derivative II; XL147derivativeII; XL147-derivative-II; N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide;SAR245408;N-[3-(Benzo[c][1,2,5]thiadiazol-5-ylaMino)quinoxalin-2-yl]-4-MethylbenzenesulfonaMide;PI3K inhibitorX
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Detailed information on the suppliers of XL-147

Properties:

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