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BGC > Product Search > 4-[4-[[2-(4-Chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide | 1257044-40-8
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Suppliers for CAS

1257044-40-8


Properties

CAS   1257044-40-8 
Formula   C45H50ClN7O7

14 Registered suppliers


Amadis Chemical Company Limited P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd) P.R.China

More details are to be found here
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Guangzhou Topwork Chemical Co., Ltd. P.R.China
Molecular Formula: C45H50ClN7O7S
Molecular Weight: 868.4392
JieJie Group Co., Ltd. P.R.China
Molecular Formula: C45H50ClN7O7S
Molecular Weight: 868.4392
Aea.ltd P.R.China
Molecular Formula: C45H50ClN7O7S
Molecular Weight: 868.4392
Molecular Formula: C45H50ClN7O7S
Molecular Weight: 868.4392
Finetech Industry Limited P.R.China
Hangzhou Lingrui Chemical Co., Ltd. P.R.China

More details are to be found here
BOC Sciences USA
Shandong SanYoung Industry Co., Ltd P.R.China
Description :
Venetoclax is a small-molecule inhibitor that has high selectivity for Bcl-2 (Ki < 0.01 nM in cell-free assays) over Mcl-1. It suppresses anti-apoptotic Bcl-2, a protein commonly overexpressed in cancer cells, to induce programmed death of CLL cells. Venetoclax is used as a second-line treatment of chronic lymphocytic leukemia (CLL).
  • Molecular Weight :868.44
Molecular Formula :
C45H50ClN7O7S
Canonical SMILES :
CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
InChI :
InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)
InChIKey :
LQBVNQSMGBZMKD-UHFFFAOYSA-N
Solubility :
10mM in DMSO
Application :
the treatment of chronic lymphocytic leukemia (CLL)
Synonyms :
ABT199; ABT-199; ABT 199; GDC0199; GDC0199; GDC 0199; RG7601; RG7601; RG 7601. Venetoclax
More details are to be found here
Carbone Scientific Co., Ltd. U.K.
Description :
Venetoclax is a small-molecule inhibitor that has high selectivity for Bcl-2 (Ki < 0.01 nM in cell-free assays) over Mcl-1. It suppresses anti-apoptotic Bcl-2, a protein commonly overexpressed in cancer cells, to induce programmed death of CLL cells. Venetoclax is used as a second-line treatment of chronic lymphocytic leukemia (CLL).
  • Molecular Weight :868.44
Molecular Formula :
C45H50ClN7O7S
Canonical SMILES :
CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
InChI :
InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)
InChIKey :
LQBVNQSMGBZMKD-UHFFFAOYSA-N
Solubility :
10mM in DMSO
Application :
the treatment of chronic lymphocytic leukemia (CLL)
Synonyms :
ABT199; ABT-199; ABT 199; GDC0199; GDC0199; GDC 0199; RG7601; RG7601; RG 7601. Venetoclax
More details are to be found here
Ambeed, Inc. USA
BLD Pharmatech Ltd P.R.China


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