BGC > Product Search > Gsk-547 | 2226735-55-1

Description :
GSK547 is a highly selective and potent RIP1 (RIPK1) inhibitor which displays 400-fold improvement in mouse pharmacokinetic oral exposure compared with GSK963.

• Molecular Weight :396.39
• Purity :≥98%

Molecular Formula :
C20H18F2N6O
Canonical SMILES :
C1CN(CCC1C(=O)N2C(CC=N2)C3=CC(=CC(=C3)F)F)C4=NC=NC(=C4)C#N
InChI :
InChI=1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1
InChIKey :
SJVGFKBLUYAEOK-SFHVURJKSA-N
Solubility :
DMSO: 100 mg/mL
Synonyms :
RIP1i

More details are to be found here