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BGC > Product Search > Alisertib | 1028486-01-2
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Suppliers for CAS

1028486-01-2


Properties

CAS   1028486-01-2 
Formula   C27H20ClFN4O4 

Structure

7 Registered suppliers


Hangzhou Keying Chem Co., Ltd. P.R.China
Capot Chemical Co., Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
JieJie Group Co., Ltd. P.R.China
Molecular Formula: C20H22N2O3
Molecular Weight: 338.40028
Aea.ltd P.R.China
Molecular Formula: C20H22N2O3
Molecular Weight: 338.40028
BOC Sciences USA
Chemos GmbH & Co. KG Germany
Description :
MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
  • Molecular Weight :518.9
  • Purity :0.98
Molecular Formula :
C27H20ClFN4O4
Canonical SMILES :
COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC
InChI :
InChI=1S/C27H20ClFN4O4/c1-36-21-5-3-4-20(29)23(21)25-19-10-15(28)6-8-17(19)24-14(12-30-25)13-31-27(33-24)32-16-7-9-18(26(34)35)22(11-16)37-2/h3-11,13H,12H2,1-2H3,(H,34,35)(H,31,32,33)
InChIKey :
ZLHFILGSQDJULK-UHFFFAOYSA-N
Appearance :
Light yellow to yellow Solid
Synonyms :
MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-.
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Properties:

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