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BGC > Product Search > INK 128 | 1224844-38-5
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Suppliers for CAS

1224844-38-5


Properties

CAS   1224844-38-5 
Formula   C15H15N7

Structure

6 Registered suppliers


Simagchem Corporation P.R.China
Dayang Chem (Hangzhou) Co.,Ltd. P.R.China
Leap Chem Co., Ltd P.R.China
Aea.ltd P.R.China
Molecular Formula: C15H15N7O
Molecular Weight: 309.3259
BOC Sciences USA
Santa Cruz Biotechnology, Inc. USA
Description :
MLN0128, also known as INK128, is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt/mTOR signaling pathway, which is frequently dysregulated in human cancers.
  • Molecular Weight :309.333
  • Purity :> 98%
Molecular Formula :
C15H15N7O
Canonical SMILES :
CC(C)N1C2=C(C(=N1)C3=CC4=C(C=C3)OC(=N4)N)C(=NC=N2)N
InChI :
InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
InChIKey :
GYLDXIAOMVERTK-UHFFFAOYSA-N
Appearance :
A crystalline solid
Synonyms :
TAK-228; TAK 228; TAK228; INK128; INK-128; INK 128; MLN0128; MLN 0128; MLN-0128; Sapanisertib.
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Detailed information on the suppliers of INK 128

Properties:

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