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Suppliers for CAS
944396-07-0
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Properties | | CAS |
944396-07-0 | | Formula |
C18H21F3N6O2 |
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13 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
More details are to be found here
Capot Chemical Co., Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C18H21F3N6O2
Molecular Weight: 410.3935496
HS Code: 29349990
Aea.ltd
P.R.China
Molecular Formula: C18H21F3N6O2
Molecular Weight: 410.3935496
HS Code: 29349990
Molecular Formula: C18H21F3N6O2
Molecular Weight: 410.3935496
HS Code: 29349990
Molecular Formula: C18H21F3N6O2
Molecular Weight: 410.3935496
HS Code: 29349990
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Molecular Formula: C18H21F3N6O2
Molecular Weight: 410.3935496
HS Code: 29349990
Finetech Industry Limited
P.R.China
More details are to be found here
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
More details are to be found here
BOC Sciences
USA
Description : BKM120, also called as buparlisib or NVP-BKM120, activity in a range of preclinical cancer models, specifically inhibits class I PI3K isoforms, which blocks p110α (IC50 = 52 nM), p110β (IC50 = 166 nM), p110δ (IC50 = 116 nM) and p110γ (IC50 = 262 nM). BKM120 displays little sensitive to Class III and Class IV PI3K's or PI4K. - Molecular Weight :410.39
- Boiling Point :645.7±65.0 °C | Condition: Press: 760 Torr
Molecular Formula : C18H21F3N6O2 Canonical SMILES : C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4
InChI :
1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
InChIKey :
CWHUFRVAEUJCEF-UHFFFAOYSA-N
Solubility :
Soluble to ≥80mg/mL in DMSO, to <1.2mg/mL in Water, to ≥22mg/mL in Ethanol
Appearance :
White to off-white solid
Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
Synonyms :
5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine; BKM120; buparlisib; NVP-BKM120; 944396-07-0; BKM 120; BKM-120; UNII-0ZM2Z182GD; 1202777-78-3; 944396-07-0; NVP-BKM120; Buparlisib; 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine; NVP-BKM-120; BKM120; BKM 120; BKM-120; UNII-0ZM2Z182GD; 1202777-78-3; CHEMBL2017974; CHEBI:71954; 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine; 5-[2,6-Di(Morpholin-4-Yl)pyrimidin-4-Yl]-4-(Trifluoromethyl)pyridin-2-Amine; C18H21F3N6O2; BKM120, BKM-120|; 2-Pyridinamine,5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-; 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-Pyridinamine
More details are to be found here
Shandong SanYoung Industry Co., Ltd
P.R.China
Description : BKM120, also called as buparlisib or NVP-BKM120, activity in a range of preclinical cancer models, specifically inhibits class I PI3K isoforms, which blocks p110α (IC50 = 52 nM), p110β (IC50 = 166 nM), p110δ (IC50 = 116 nM) and p110γ (IC50 = 262 nM). BKM120 displays little sensitive to Class III and Class IV PI3K's or PI4K. - Molecular Weight :410.39
- Boiling Point :645.7±65.0 °C | Condition: Press: 760 Torr
Molecular Formula : C18H21F3N6O2 Canonical SMILES : C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4
InChI :
1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
InChIKey :
CWHUFRVAEUJCEF-UHFFFAOYSA-N
Solubility :
Soluble to ≥80mg/mL in DMSO, to <1.2mg/mL in Water, to ≥22mg/mL in Ethanol
Appearance :
White to off-white solid
Storage : Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
Synonyms :
5-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine; BKM120; buparlisib; NVP-BKM120; 944396-07-0; BKM 120; BKM-120; UNII-0ZM2Z182GD; 1202777-78-3; 944396-07-0; NVP-BKM120; Buparlisib; 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine; NVP-BKM-120; BKM120; BKM 120; BKM-120; UNII-0ZM2Z182GD; 1202777-78-3; CHEMBL2017974; CHEBI:71954; 5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine; 5-[2,6-Di(Morpholin-4-Yl)pyrimidin-4-Yl]-4-(Trifluoromethyl)pyridin-2-Amine; C18H21F3N6O2; BKM120, BKM-120|; 2-Pyridinamine,5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-; 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-Pyridinamine
More details are to be found here
Allfluoro Pharmaceutical Co. Ltd.
P.R.China
MDL: MFCD18251596
MF: C18H21F3N6O2
MW: 410,39
other name: 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
Chemos GmbH & Co. KG
Germany
MDL: MFCD18251596
MF: C18H21F3N6O2
MW: 410,39
other name: 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
Santa Cruz Biotechnology, Inc.
USA
MDL: MFCD18251596
MF: C18H21F3N6O2
MW: 410,39
other name: 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine
Detailed information on the suppliers of
BKM120 |
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