BGC > Product Search > Loxiglumide | 107097-80-3

Molecular Formula: C21H30Cl2N2O5
Molecular Weight: 461.38
Hazard Symbols: Xn
WGKGermany: 3

Molecular Formula: C21H30Cl2N2O5
Molecular Weight: 461.38
Hazard Symbols: Xn
WGKGermany: 3

Description :
Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.

• Molecular Weight :461.38
• Boiling Point :632.2±55.0 °C | Condition: Press: 760 Torr
• Melting Point :113-115 °C
• Purity :95%

Molecular Formula :
C21H30Cl2N2O5
Canonical SMILES :
CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)C1=CC(=C(C=C1)Cl)Cl
InChI :
InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)
InChIKey :
QNQZBKQEIFTHFZ-UHFFFAOYSA-N
Solubility :
DMSO: ≥5 mg/mL
Appearance :
White to beige powder
Application :
Loxiglumide stimulates calorie intake and hunger feelings in humans. It inhibits pancreatic secretion of digestive enzymes.
Storage : 2-8°C
Synonyms :
CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid

More details are to be found here

Description :
Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.

• Molecular Weight :461.38
• Boiling Point :632.2±55.0 °C | Condition: Press: 760 Torr
• Melting Point :113-115 °C
• Purity :95%

Molecular Formula :
C21H30Cl2N2O5
Canonical SMILES :
CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)C1=CC(=C(C=C1)Cl)Cl
InChI :
InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)
InChIKey :
QNQZBKQEIFTHFZ-UHFFFAOYSA-N
Solubility :
DMSO: ≥5 mg/mL
Appearance :
White to beige powder
Application :
Loxiglumide stimulates calorie intake and hunger feelings in humans. It inhibits pancreatic secretion of digestive enzymes.
Storage : 2-8°C
Synonyms :
CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid

More details are to be found here

Description :
Loxiglumide is an orally active, potent and selective small-molecule antagonist of the cholecystokinin receptor CCKA. It stimulates calorie intake and hunger feelings in humans. It could antagonize the CCK-induced reduction of gastric emptying in rats, accelerate the intestinal transport and accelerate the gallbladder emptying in mice. It inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.

• Molecular Weight :461.38
• Boiling Point :632.2±55.0 °C | Condition: Press: 760 Torr
• Melting Point :113-115 °C
• Purity :95%

Molecular Formula :
C21H30Cl2N2O5
Canonical SMILES :
CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)C1=CC(=C(C=C1)Cl)Cl
InChI :
InChI=1S/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)
InChIKey :
QNQZBKQEIFTHFZ-UHFFFAOYSA-N
Solubility :
DMSO: ≥5 mg/mL
Appearance :
White to beige powder
Application :
Loxiglumide stimulates calorie intake and hunger feelings in humans. It inhibits pancreatic secretion of digestive enzymes.
Storage : 2-8°C
Synonyms :
CR-1505; CR 1505; CR1505; D,L-4-(3,4-dichlorobenzoylamino)-5-(n-3-methoxypropylpentylamino)-5-oxo-pentanoicacid;Pentanoicacid,4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino);CR-1505;CR1505;4-(3,4-Dichlorobenzamido)-5-((3-methoxypropyl)(pentyl)amino)-5-oxopentanoic acid

More details are to be found here