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Suppliers for CAS
932986-18-0
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Properties | CAS |
932986-18-0 | Formula |
C15H17ClN2OS |
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3 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C15H17ClN2OS Molecular Weight: 308.82628
Aea.ltd
P.R.China
Molecular Formula: C15H17ClN2OS Molecular Weight: 308.82628
BOC Sciences
USA
Description : Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. - Molecular Weight :308.82
- Purity :> 98%
Molecular Formula : C15H17ClN2OS Canonical SMILES : CCCC(=O)NCCC1=CSC(=N1)C2=CC=C(C=C2)Cl InChI : InChI=1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19) InChIKey : VYBFWKKCWTXCQX-UHFFFAOYSA-N Solubility : DMSO: 36 mg/mL Appearance : White to beige powder Storage : 2-8ºC Synonyms : N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide
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Azoramide
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Last update 2024-04-25
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