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Suppliers for CAS
1338225-97-0
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Properties | | CAS |
1338225-97-0 | | Formula |
C17H11ClF3N5O3 |
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6 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C17H11ClF3N5O3
Molecular Weight: 425.7491496
Chemvon Biotechnology Co. Ltd.
P.R.China
Molecular Formula: C17H11ClF3N5O3
Molecular Weight: 425.7491496
Aea.ltd
P.R.China
Molecular Formula: C17H11ClF3N5O3
Molecular Weight: 425.7491496
Molecular Formula: C17H11ClF3N5O3
Molecular Weight: 425.7491496
BOC Sciences
USA
Description : Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going. - Molecular Weight :425.75
- Purity :98%
Molecular Formula : C17H11ClF3N5O3 Canonical SMILES : Cn1c(n[nH]c1=O)Cn2ccc(c(c2=O)Oc3cc(cc(c3)Cl)C#N)C(F)(F)F
InChI :
1S/C17H11ClF3N5O3/c1-25-13(23-24-16(25)28)8-26-3-2-12(17(19,20)21)14(15(26)27)29-11-5-9(7-22)4-10(18)6-11/h2-6H,8H2,1H3,(H,24,28)
InChIKey :
ZIAOVIPSKUPPQW-UHFFFAOYSA-N
Solubility :
Soluble in DMSO
Appearance :
Powder
Application :
HIV-1 infections
Storage : -20°C Freezer
Synonyms :
MK-1439; MK 1439; MK1439; MK-1439-019;3-Chloro-5-((1-((4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl)oxy)benzonitrile
More details are to be found here
Detailed information on the suppliers of
Doravirine |
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