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Suppliers for CAS
2628280-40-8
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Properties | | CAS |
2628280-40-8 |
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8 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Jinan Honestpharm Co., Ltd
P.R.China
XD BIOCHEMS Ltd
P.R.China
Aea.ltd
P.R.China
Nantong Xindao Biotech Ltd
P.R.China
BOC Sciences
USA
Description : PF-07321332 is an orally available SARS-CoV 3C-like protease (3CLPRO) inhibitor. 3C-like protease (3CLPRO) is the main protease found in coronaviruses, which cleaves the coronavirus polyprotein at eleven conserved sites. PF-07321332 has demonstrated oral activity in a mouse-adapted SARS-CoV-2 model and has achieved oral plasma concentrations exceeding the in vitro antiviral cell potency in a phase I clinical trial in healthy human participants. - Molecular Weight :499.53
- Purity :98%
Molecular Formula : C23H32F3N5O4 Canonical SMILES : CC1(C2C1C(N(C2)C(=O)C(C(C)(C)C)NC(=O)C(F)(F)F)C(=O)NC(CC3CCNC3=O)C#N)C
InChI :
InChI=1S/C23H32F3N5O4/c1-21(2,3)16(30-20(35)23(24,25)26)19(34)31-10-13-14(22(13,4)5)15(31)18(33)29-12(9-27)8-11-6-7-28-17(11)32/h11-16H,6-8,10H2,1-5H3,(H,28,32)(H,29,33)(H,30,35)/t11-,12-,13-,14-,15-,16+/m0/s1
InChIKey :
LIENCHBZNNMNKG-OJFNHCPVSA-N
Solubility :
In vitro: 10 mM in DMSO
Appearance :
White to Off-white Solid
Storage : -20°C
Synonyms :
PF 07321332; PF07321332
More details are to be found here
WITEGA Laboratorien Berlin-Adlershof GmbH
Germany
Description : PF-07321332 is an orally available SARS-CoV 3C-like protease (3CLPRO) inhibitor. 3C-like protease (3CLPRO) is the main protease found in coronaviruses, which cleaves the coronavirus polyprotein at eleven conserved sites. PF-07321332 has demonstrated oral activity in a mouse-adapted SARS-CoV-2 model and has achieved oral plasma concentrations exceeding the in vitro antiviral cell potency in a phase I clinical trial in healthy human participants. - Molecular Weight :499.53
- Purity :98%
Molecular Formula : C23H32F3N5O4 Canonical SMILES : CC1(C2C1C(N(C2)C(=O)C(C(C)(C)C)NC(=O)C(F)(F)F)C(=O)NC(CC3CCNC3=O)C#N)C
InChI :
InChI=1S/C23H32F3N5O4/c1-21(2,3)16(30-20(35)23(24,25)26)19(34)31-10-13-14(22(13,4)5)15(31)18(33)29-12(9-27)8-11-6-7-28-17(11)32/h11-16H,6-8,10H2,1-5H3,(H,28,32)(H,29,33)(H,30,35)/t11-,12-,13-,14-,15-,16+/m0/s1
InChIKey :
LIENCHBZNNMNKG-OJFNHCPVSA-N
Solubility :
In vitro: 10 mM in DMSO
Appearance :
White to Off-white Solid
Storage : -20°C
Synonyms :
PF 07321332; PF07321332
More details are to be found here
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details