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Suppliers for CAS
1260907-17-2
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Properties | | CAS |
1260907-17-2 | | Formula |
C22H22ClN5O2 |
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5 Registered suppliers
Amadis Chemical Company Limited
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C22H22ClN5O2
Molecular Weight: 423.89538
Aea.ltd
P.R.China
Molecular Formula: C22H22ClN5O2
Molecular Weight: 423.89538
Finetech Industry Limited
P.R.China
More details are to be found here
BOC Sciences
USA
Description : GSK525762A, also known as I-BET-762 and GSK525762, is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity. Upon administration, the BET inhibitor GSK525762 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, BET proteins, comprising of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth. Molecular Formula : C22H22ClN5O2 Canonical SMILES : CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
InChI :
InChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1
InChIKey :
AAAQFGUYHFJNHI-SFHVURJKSA-N
Appearance :
white solid powder
Synonyms :
GSK525762; GSK525762; GSK525762; GSK525762A; GSK-525762A; GSK 525762A; I-BET-762; I-BET762; I-BET 762; molibresib
More details are to be found here
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