BGC > Product Search > Tirapazamine

Molecular Formula: C7H6N4O2
Molecular Weight: 178,15

Molecular Formula: C7H6N4O2
Molecular Weight: 178,15

Description :
Tirapazamine is a benzotriazine di-N-oxide with potential antineoplastic activity. Tirapazamine is selectively activated by multiple reductases to form free radicals in hypoxic cells, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. This agent also sensitizes hypoxic cells to ionizing radiation and inhibits the repair of radiation-induced DNA strand breaks via inhibition of topoisomerase II. Check for active clinical trials or closed clinical trials using this agent.

• Molecular Weight :178.15
• Purity :0.98

Molecular Formula :
C7H6N4O2
Canonical SMILES :
C1=CC=C2C(=C1)N(C(=N)N=[N+]2[O-])O
InChI :
InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4,8,12H
InChIKey :
QVMPZNRFXAKISM-UHFFFAOYSA-N
Synonyms :
US brand name: Tirazone. Code names: SR 4233. WIN 59075. SR-259075, NSC-130181, Win-59075, SR-4233.

More details are to be found here