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BGC > Product Search > Avapritinib(blu-285) | 1703793-34-3
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Suppliers for CAS

1703793-34-3


Properties

CAS   1703793-34-3 

7 Registered suppliers


Amadis Chemical Company Limited P.R.China
Leap Chem Co., Ltd P.R.China
JieJie Group Co., Ltd. P.R.China
Molecular Formula: C26H27FN10
Molecular Weight: 498.5579832
Aea.ltd P.R.China
Molecular Formula: C26H27FN10
Molecular Weight: 498.5579832
Finetech Industry Limited P.R.China
BOC Sciences USA
Chemtour Biotech Co., Ltd P.R.China
Description :
BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis.
  • Molecular Weight :498.56
Molecular Formula :
C26H27FN10
Canonical SMILES :
CC(C1=CC=C(C=C1)F)(C2=CN=C(N=C2)N3CCN(CC3)C4=NC=NN5C4=CC(=C5)C6=CN(N=C6)C)N
InChI :
InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1
InChIKey :
DWYRIWUZIJHQKQ-SANMLTNESA-N
Solubility :
DMSO:≥ 83.33 mg/mL
Synonyms :
(1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297
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Detailed information on the suppliers of Avapritinib(blu-285)

Properties:

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