BGC > Product Search > (S)-6-((1-Acetylpiperidin-4-yl)amino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)pyrimidine-4-carboxamide | 1616392-22-3

Molecular Formula: C24H32N6O3
Molecular Weight: 452.54928

Molecular Formula: C24H32N6O3
Molecular Weight: 452.54928

Description :
GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models and has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma.

• Molecular Weight :452.55
• Boiling Point :760.3±60.0 ℃ at 760 Torr

Molecular Formula :
C24H32N6O3
Canonical SMILES :
CC(=O)N1CCC(CC1)NC2=NC=NC(=C2)C(=O)NCC(CN3CCC4=CC=CC=C4C3)O
InChI :
InChI=1S/C24H32N6O3/c1-17(31)30-10-7-20(8-11-30)28-23-12-22(26-16-27-23)24(33)25-13-21(32)15-29-9-6-18-4-2-3-5-19(18)14-29/h2-5,12,16,20-21,32H,6-11,13-15H2,1H3,(H,25,33)(H,26,27,28)/t21-/m0/s1
InChIKey :
JLCCNYVTIWRPIZ-NRFANRHFSA-N
Solubility :
DMSO: ≥ 30 mg/mL
Appearance :
White to Yellow Solid
Storage : Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms :
GSK-3326595; GSK 3326595; GSK3326595; EPZ015938; EPZ 015938; EPZ-015938; 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide

More details are to be found here

Purity : 98%
Smile code : O=C(C1=NC=NC(NC2CCN(C(C)=O)CC2)=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
MDL Number : MFCD29991177
MolFormula : C24H32N6O3
MolWeight : 452.5493
Available in stock : 8.839

More details are to be found here

Smile code:
O=C(C1=NC=NC(NC2CCN(C(C)=O)CC2)=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
MDL Number:
MFCD29991177
Purity :
98%
Available in stock:
18.633 g

More details are to be found here